Publications
2025
Moon, H. & Chen, X. (2025). Plasma p-tau217 predicting brain-wide tau accumulation in preclinical AD. The Journal of Prevention of Alzheimer's Disease, 100252. [Article]
Chen, X., Juarez, A., Mason, S., Kobayashi, S., Baker, S. L., Harrison, T. M., Landau, S. M., & Jagust, W. J. (2025). Longitudinal relationships between Aβ and tau to executive function and memory in cognitively normal older adults. Neurobiology of Aging, 145, 32-41. [Article]
Han, F., Chen, X., Murphy, A., Lee, J.Q., Ziontz, J., Landau, S.M., Baker, S.L., Harrison, T.M., & Jagust, W.J. (2025). Patterns of pathological tau deposition reflect the dynamics of cortical brain activity. Cell Reports, 44(7), 11583. [Article]
Pezzoli, S., Giorgio, J., Chen, X., Ward, T. J., Harrison, T. M., & Jagust, W. J. (2025). Cognitive aging outcomes are related to both tau pathology and maintenance of cingulate cortex structure. Alzheimer's & Dementia, 21, e14515. [Article]
Park, D. C., Hennessee, J. P., Smith, E. T., Chan, M. Y., Chen, X., Dakanali, M., Farrell, M. E., Liu, P., Lu, H., Rofsky, N., Sun, X., Tamminga, C., Moore, W., Kennedy, K. M., Rodrigue, K., & Wig, G. S. (2025). The Dallas Lifespan Brain Study: a comprehensive adult lifespan data set of brain and cognitive aging. Scientific Data, 12(1), 1-14. [Article]
Giorgio, J., Soleimani-Meigooni, D. N., Janabi, M., Baker, S. L., Chen, X., Toueg, T. N., ... & Jagust, W. J. (2025). Imaging synaptic density in aging and Alzheimer Disease with [18F] SynVesT-1. Journal of Nuclear Medicine, 66(4), 620-625. [Article]
2024
Chen, X., Toueg, T. N., Harrison, T. M., Baker, S. L., & Jagust, W. J. (2024). Regional tau deposition reflects different pathways of subsequent neurodegeneration and memory decline in cognitively normal older adults. Annals of Neurology, 95(2), 249-259. [Article]
Chen, X., Gupta, S., Russo, S., Sitzia, G., Westbrook, A., & White, S. R. (2024). Including early career researchers in scientific publishing. Journal of Neuroscience, 44(23). [Article]
Han, F., Lee, J.Q., Chen, X., Ziontz, J., Ward, T., Landau, S.M., Baker, S.L., Harrison, T.M., & Jagust, W.J. (2025). Global activity and its coping with cerebrospinal fluid flow is related to tau pathology. Alzheimer's & Dementia, 20(12), 8541-8555. [Article]
Ziontz, J., Harrison, T. M., Chen, X., Giorgio, J., Adams, J. N., Wang, Z., ... & Alzheimer’s Disease Neuroimaging Initiative. (2024). Behaviorally meaningful functional networks mediate the effect of Alzheimer’s pathology on cognition. Cerebral Cortex, 34(4), bhae134. [Article]
Smith, E. T., Nashiro, K., O’Connell, M., Chen, X., & Basak, C. (2024). Cognitive and gray matter volume predictors of learning across two types of casual video games in older Adults: Action vs Strategy. Aging Brain, 6, 100131. [Article]
2023
Cassady, K. E., Chen, X., Adams, J. N., Harrison, T. M., Zhuang, K., Maass, A., Baker, S., & Jagust, W. J. (2023). Effect of Alzheimer's pathology on task-related brain network reconfiguration in aging. Journal of Neuroscience, 43(38), 6553-6563. [Article]
Munro, C. E., Boyle, R., Chen, X., Coughlan, G., Gonzalez, C., Jutten, R., Martinez, J., Orlovsky, I., Robinson, T., Weizenbaum, E., Pluim, C., Quiroz, Y., Gatchel, J., Vannini, P., & Amariglio, R. (2023). Recent contributions to the field of subjective cognitive decline: a review. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 15:e12475. [Article]
2022
Chen, X., Rundle, M. M., Kennedy, K. M., Moore, W., & Park, D. C. (2022). Functional activation features of memory in successful agers across the adult lifespan. NeuroImage, 257, 119276. [Article]
Chen, X., Varghese, L., & Jagust, W. J. (2022). A Double-Edged Sword: The Role of Prior Knowledge in Memory Aging. Frontiers in Aging Neuroscience, 14. [Article]
Zhuang, K., Chen, X., Cassady, K. E., Baker, S. L., & Jagust, W. J. (2022). Metacognition, cortical thickness, and tauopathy in aging. Neurobiology of Aging, 118, 44-54. [Article]
Hennessee, J. P., Webb, C. E., Chen, X., Kennedy, K. M., Wig, G. S., & Park, D. C. (2022). Relationship of prefrontal brain lateralization to optimal cognitive function differs with age. NeuroImage, 264, 119736. [Article]
2021
Chen, X., Cassady, K. E., Adams, J. N., Harrison, T. M., Baker, S. L., & Jagust, W. J. (2021). Regional tau effects on prospective cognitive change in cognitively normal older adults. Journal of Neuroscience, 41(2), 366-375. [Article]
Chen, X., Farrell, M. E., Rundle, M. M., Chan, M. Y., Moore, W., Wig, G. S., & Park, D. C. (2021). The relationship of functional hippocampal activity, amyloid deposition, and longitudinal memory decline to memory complaints in cognitively healthy older adults. Neurobiology of Aging, 105, 318-326. [Article]
Cassady, K. E., Adams, J. N., Chen, X., Maass, A., Harrison, T. M., Landau, S., Baker, S., & Jagust, W. (2021). Alzheimer’s pathology is associated with dedifferentiation of intrinsic functional memory networks in aging. Cerebral Cortex, 31(10), 4781-4793. [Article]
2019
Chen, X., Farrell, M. E., Moore, W., & Park, D. C. (2019). Actual memory as a mediator of the amyloid-subjective cognitive decline relationship. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 11, 151-160. [Article]
Zhang, M., Chen, X., & Liu, X. L. (2019). Confidence in accuracy moderates the benefits of retrieval practice. Memory, 27(4), 548-554. [Article]
Chen, X., Zhang, M., & Liu, X. L. (2019). Retrieval practice facilitates judgments of learning through multiple mechanisms: Simultaneous and independent contribution of retrieval confidence and retrieval fluency. Frontiers in Psychology, 10, 987. [Article]
2018
Farrell, M. E., Chen, X., Rundle, M. M., Chan, M. Y., Wig, G. S., & Park, D. C. (2018). Regional amyloid accumulation and cognitive decline in initially amyloid-negative adults. Neurology, 91(19), e1809-e1821. [Article]
Peng, S. L., Chen, X., Li, Y., Rodrigue, K. M., Park, D. C., & Lu, H. (2018). Age-related changes in cerebrovascular reactivity and their relationship to cognition: a four-year longitudinal study. NeuroImage, 174, 257-262. [Article]
De Vis, J. B., Peng, S. L., Chen, X., Li, Y., Liu, P., Sur, S., Rodrigue, K. M., Park, D. C., & Lu, H. (2018). Arterial‐spin‐labeling (ASL) perfusion MRI predicts cognitive function in elderly individuals: a 4‐year longitudinal study. Journal of Magnetic Resonance Imaging, 48(2), 449-458. [Article]
Song, Z., Farrell, M. E., Chen, X., & Park, D. C. (2018). Longitudinal accrual of neocortical amyloid burden is associated with microstructural changes of the fornix in cognitively normal adults. Neurobiology of Aging, 68, 114-122. [Article]
2017
Chen, X., Hertzog, C., & Park, D. C. (2017). Cognitive predictors of everyday problem solving across the lifespan. Gerontology, 63(4), 372-384. [Article]
Farrell, M. E., Kennedy, K. M., Rodrigue, K. M., Wig, G., Bischof, G. N., Rieck, J. R., Chen, X., Festini, S. B., Devous, M. D., & Park, D. C. (2017). Association of longitudinal cognitive decline with amyloid burden in middle-aged and older adults: evidence for a dose-response relationship. JAMA Neurology, 74(7), 830-838. [Article]